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Tag: biotech

The Background of Circular RNA Synthesis

The Background of Circular RNA Synthesis

Posted on August 29, 2023August 29, 2023 by alexbrown

In recent years, nucleic acid therapy involving various types of ribonucleic acids (RNAs), including messenger RNA (mRNA), small interfering RNA (siRNA), and microRNA (miRNA), has rapidly emerged as a newRead More

PEG cGMP Manufacture: From Material Preparation to Quality Control

PEG cGMP Manufacture: From Material Preparation to Quality Control

Posted on August 29, 2023August 29, 2023 by alexbrown

PEG manufacturing (Polyethylene Glycol) involves several steps and processes. Here is a general outline of how to conduct PEG manufacturing in a cGMP (current Good Manufacturing Practices) compliant facility: Raw materialRead More

Bioconjugation Strategies for Enhancing Drug Delivery and Therapeutic Efficacy

Bioconjugation Strategies for Enhancing Drug Delivery and Therapeutic Efficacy

Posted on August 29, 2023August 29, 2023 by alexbrown

In recent years, bioconjugation has emerged as a powerful strategy for improving drug delivery and enhancing therapeutic efficacy. By linking drugs to various biological entities, such as proteins, antibodies, nanoparticles,Read More

ADC Cleavable Linker: Classification and Mechanism of Action

ADC Cleavable Linker: Classification and Mechanism of Action

Posted on August 29, 2023August 29, 2023 by alexbrown

Antibody-drug conjugates (ADCs), as emerging anticancer drugs, can deliver highly cytotoxic molecules directly to cancer cells to kill them. ADC is a monoclonal antibody covalently bound to cytotoxic chemical substancesRead More

Fermentation Production of ADC Payloads

Fermentation Production of ADC Payloads

Posted on August 29, 2023August 29, 2023 by alexbrown

Targeted therapies have significantly advanced the field of cancer therapy, and among these, antibody-drug conjugates (ADCs) have emerged as a viable therapeutic strategy. ADCs increase efficacy and decrease systemic toxicityRead More

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